Here's the page about Time Away settings:
https://www.ebay.com/help/selling/selling-tools/time-away?id=5137
If you allow sales while away, make sure you read all the exclusions carefully.
There's an option to set up an out of office auto-response to messages within the Time Away settings.
Keep in mind you're still responsible for handling any return requests, claims or payment disputes that are filed while you're away. If you won't have internet access to check in every day or two, I suggest setting up automated return rules. You can turn off the automation after you return.
https://www.ebay.com/rtn/Return/SellerRules
